Kisii town, like other major towns in Kenya, has suburbs located on the outskirts of the town, primarily residential settlements where the inhabitants live and work.
Notable areas include:
- Nyanchwa
- Jogoo
- Daraja Mbili
- Mwembe
- Nyakongo
- Nyangena
- Gesonso
- Nyamataro
- Bochura
- Suneka
- Egesa
- Menyinkwa
- Gekomu
- Getare
- Nyakoe
- Mosocho
- Keumbu
- Bobaracho
- Kegati
- Omogonchoro